Welcome, Dear Visitors!
In our online pharmacy each customer can find a wide variety of any necessary medicines for therapy and prevention health care.
Basic principles of 100Drugs.Com are professionalism, reliability, guaranteed quality of the medicines, attentive and immediate service. We offer qualified medicines keeping prices on the minimal level.
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Viagra
(Sildenafil Citrate)
per pill
$1.15

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Cialis
(Generic Tadalafil)
per pill
$1.98

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Liton
per item
$16.26

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Dermovate
per item
$17.60

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Topamax
(Generic Topiramate)
per pill
$0.42

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Zineryt
per bottle
$23.80

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Generic Drugs – How Are They Proved
Generic drugs are exact re-creates of patented drug molecules permitted to be manufactured and marketed by FDA and other respective agencies in specific cases where exclusivity of branded drugs are either challenged or they are invalid or have expired. For benefit of those who are misled by vociferous campaigns, it would be safe state that generic drugs or cheap drugs are replicates of brand drugs and are equivalent of them in every practical respects. The scientific metrics in use to tell whether generic drugs are equivalent are bioequivalence and therapeutic equivalence.
Bioequivalence and Therapeutic Equivalence of Generic Drugs
First of all, let’s understand what do these terms actually mean. Bioequivalence is a term that stands to signify that two drugs are same and concurrent in dosage, effects & side effects, dosage, way of administration, safety and potency. In the same way if the resulting effects after administering it are exact same for the second drug as that of branded drug then you have established its therapeutic equivalence.
How Are Bioequivalence and Therapeutic Equivalence Established
USFDA or its counterparts in their respective countries have laid out regulations that govern drug approval regardless of whether they are new or generic drugs. Generic drugs are required to be tested and proven in the exact same as brand-name drugs to establish their equivalence in dosage, effects, side effects, intended use, administration, safety/risks, and potency as their original counterparts. All these tests are done first during the developmental stages at laboratories and later when ready for approval application, they are tested clinically over extended periods on wide ranging patients at varied conditions. All critical parameters like how the generic drugs behave environmentally controlled different conditions while monitoring their physical and chemical stabilities (or the lack of it) before they are ready for clinical trials. When generic drugs pass this stage you can say that they have successfully established their bioequivalence with original drugs. In other words, their pharmacological effects are exactly the same as those of their brand-name counterparts.
Clinical trials monitor parameters like the drugs’ dispersion time, therapeutic and physiological effects and side effects which prove therapeutic equivalence.
Aren’t There Differences between Generic Drugs and Brand-Name Drugs At All
Law requires that both generic drugs and branded drugs have same quality but permits differences in unimportant circles such as colors, shapes, flavors and packaging. Particularly, these are brand building part of any products and have nothing to do with efficacy of products. Moreover these are issues related to trademark and no two companies would like to have similar looking products, no matter whether it is generic drugs or original drugs.
I would encourage anyone concerned about generic drugs to consult a physician as well as USFDA which helps dispel any doubt whatsoever. The fact that generic drugs are considerably cheaper should not give way for unduly concerns as there are many things outside pricing strategies that decide quality. In a nutshell it is not wise attaching quality with price and generic tag.
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