Fosamax

What is Fosamax?

Fosamax is an inhibitor of bone resorption in osteoporosis. Alendronate sodium, the active component of the drug, belongs to a group of medicines called bisphosphonates, which being localized in areas of active bone resorption under osteoclasts, inhibit the process of osseous tissues atrophy, having no direct influence on formation of new bones. Being initially developed by Merk and marketed under the trade name Fosamax, Alendronate is now available in a variety of generic versions of various dosage strength after the expiration of Merck’s patent in 2008.

How does Fosamax work?

During the treatment with generic Fosamax normal bone tissues are deposited with Alendronate being embedded in the bone matrix, remaining pharmacologically inactive. Long-term Fosamax therapy contributes to bone mass gain, to normalization of bone metabolism, to bone mineral density increasing, especially concerning lumbar spine, femoral neck and greater trochanter. The drug reduces the incidence of fractures in those parts of the skeletal system that are more exposed to osteoporosis development and its sequellae, these are vertebral column and femur.

What are Fosamax uses?

Generic Fosamax is more commonly indicated to treat osteoporosis in postmenopausal women to prevent fractures; it is widely used as a preventive treatment in women after menopause, who are at higher risk of osteoporosis development. Though men are less prone to osteoporosis they also suffer from this disease, and Fosamax has been proven to be effective in men regardless their age and sexual gland functioning.

What is the recommended Fosamax dosage?

Fosamax is necessary to be taken in fasted state at least half an hour prior to first food intake with sufficient quantity of plain water; otherwise its bioavailability is significantly reduced. A tablet must be swallowed in whole! Do not chew a tablet or resolve it in the mouth cavity! Stay awake after the drug administration; do not lie down to avoid irritation of esophageal mucosa. Simultaneous intake with coffee or orange juice makes the drug absolutely ineffective. Fosamax is intended for long-term use. Alendronate 70 mg is a sufficient weekly dose to achieve expected therapeutic effect. In any case it is strongly recommended to have a consultation of a medical specialist prior to buying generic Fosamax.

Where can a patient buy Fosamax?

Beginning the treatment with Fosamax a patient should be aware of the expenses he will bear during the course, as the drug is not the cheapest one and the therapy duration is not short-termed. When estimated all pros and cons it may be evident that ordering Fosamax online is the only acceptable option, because online pharmacies usually offer large-order discounting and free shipping.