THE PREPARATION DESCRIPTION IS NOT INTENDED FOR
MEDICATION WITHOUT PARTICIPATION OF THE DOCTOR!

Therapeutic actions: Celebrex(celecoxib) belongs to a group of medicines called NSAID (non-steroidal anti-inflammatory drug). Celebrex inhibits the enzyme COX2( cyclooxigenase-2) resulting in inhibiting the production of inflammatory mediators called prostoglandins. Thus, Celebrex exerts anti-inflammatory and moderate analgesic effects.

Contraindications and cautions: Celebrex should not be used in the following conditions:

• Allergy to any of the medication ingredients or allergy to sulfa medicines.
• Tendency to skin allergic reactions, bronchial asthma, hives, intolerance of NSAID's
• Third pregnancy trimester
• Breastfeeding

Necessarily let your health care provider know in the following conditions:

• Cardiovascular diseases(congestive heart failure, hypertension)
• Liver diseases(liver failure)
• Diabetes
• Bleedings of a different origin
• Kidney disease(kidney failure)
• Stomach ulcers

Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Celebrex will experience it or any other.

• The most common side effects include:
• Gastrointestinal tract: abdominal pain, diarrhea, dyspepsia, meteorism,
• CNS: headache, dizziness, drowsiness
• Other: swelling of the arms or legs, runny nose, sore throat, cold and flu symptoms, skin rash

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with Celebrex, please read the information provided with Celebrex or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Celebrex. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.

Celebrex is indicated in the following conditions:

• ACE inhibitors
• NSAID's (Aspirin)
• Anti fungal agents(fluconazole)
• Water pills(Lasix, thiazide diuretics)
• Lithium
• Warfarin